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both the 100L and 180L are stellar lenses. The “best” for macro is the 180 as you get a longer working distance, problem is however it is not hand holdable. If you’re happy to use a tripod and preferably a macro rail for focus stacking by all means, you will not be disappointed. If you have space it works really well for portraits as well. The 100L has the advantage of shorter focal length combined with IS making it reasonable to hand hold for macro work but you are much more likely to scare away small critters and having to sort out more light as standing closer you may well end up blocking natural light.